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Cognitive Decline in Preclinical Alzheimer’s Disease: Amyloid-Beta versus Tauopathy
We perform a large-scale meta-analysis of 51 peer-reviewed 3xTg-AD mouse publications to compare Alzheimer’s disease (AD) quantitative clinical outcome measures, including amyloid-β (Aβ), total tau, and phosphorylated tau (pTau), with cognitive performance in Morris water maze (MWM) and Novel Objec...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734131/ https://www.ncbi.nlm.nih.gov/pubmed/29154274 http://dx.doi.org/10.3233/JAD-170490 |