Cargando…

Cognitive Decline in Preclinical Alzheimer’s Disease: Amyloid-Beta versus Tauopathy

 We perform a large-scale meta-analysis of 51 peer-reviewed 3xTg-AD mouse publications to compare Alzheimer’s disease (AD) quantitative clinical outcome measures, including amyloid-β (Aβ), total tau, and phosphorylated tau (pTau), with cognitive performance in Morris water maze (MWM) and Novel Objec...

Descripción completa

Detalles Bibliográficos
Autores principales: Huber, Colin M., Yee, Connor, May, Taylor, Dhanala, Apoorva, Mitchell, Cassie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734131/
https://www.ncbi.nlm.nih.gov/pubmed/29154274
http://dx.doi.org/10.3233/JAD-170490