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Nuclear Localization of Apolipoprotein E4: A New Trick for an Old Protein

One of the most important genetic risk factors for late-onset Alzheimer’s Disease (AD) is harboring the ApoE4 allele. Much is known regarding the functions of the ApoE4 protein including cholesterol transport in the CNS and a critical role in clearing beta-amyloid deposits in the AD brain. However,...

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Detalles Bibliográficos
Autores principales: Rohn, Troy T, Moore, Zachary D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734658/
https://www.ncbi.nlm.nih.gov/pubmed/29264400
http://dx.doi.org/10.23937/2378-3001/1410067