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Nuclear Localization of Apolipoprotein E4: A New Trick for an Old Protein
One of the most important genetic risk factors for late-onset Alzheimer’s Disease (AD) is harboring the ApoE4 allele. Much is known regarding the functions of the ApoE4 protein including cholesterol transport in the CNS and a critical role in clearing beta-amyloid deposits in the AD brain. However,...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734658/ https://www.ncbi.nlm.nih.gov/pubmed/29264400 http://dx.doi.org/10.23937/2378-3001/1410067 |