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Roles of claudin-2, ZO-1 and occludin in leaky HK-2 cells

BACKGROUND: Claudin-2, ZO-1, and occludin are major components of tight junctions (TJs) in the proximal tubule. However, their roles in maintaining paracellular permeability as leaky epithelia have yet to be defined. METHODS: To investigate the contributory role of TJ proteins in the leaky proximal...

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Detalles Bibliográficos
Autores principales: Kim, Sua, Kim, Gheun-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734727/
https://www.ncbi.nlm.nih.gov/pubmed/29252987
http://dx.doi.org/10.1371/journal.pone.0189221