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Roles of claudin-2, ZO-1 and occludin in leaky HK-2 cells
BACKGROUND: Claudin-2, ZO-1, and occludin are major components of tight junctions (TJs) in the proximal tubule. However, their roles in maintaining paracellular permeability as leaky epithelia have yet to be defined. METHODS: To investigate the contributory role of TJ proteins in the leaky proximal...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734727/ https://www.ncbi.nlm.nih.gov/pubmed/29252987 http://dx.doi.org/10.1371/journal.pone.0189221 |