Molecular dynamics simulation unveils the conformational flexibility of the interdomain linker in the bacterial transcriptional regulator GabR from Bacillus subtilis bound to pyridoxal 5’-phosphate

GabR from Bacillus subtilis is a transcriptional regulator belonging to the MocR subfamily of the GntR regulators. The structure of the MocR regulators is characterized by the presence of two domains: i) a N-terminal domain, about 60 residue long, possessing the winged-Helix-Turn-Helix (wHTH) archit...

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Detalles Bibliográficos
Autores principales: Milano, Teresa, Gulzar, Adnan, Narzi, Daniele, Guidoni, Leonardo, Pascarella, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734734/
https://www.ncbi.nlm.nih.gov/pubmed/29253008
http://dx.doi.org/10.1371/journal.pone.0189270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734734/
https://www.ncbi.nlm.nih.gov/pubmed/29253008
http://dx.doi.org/10.1371/journal.pone.0189270

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