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Molecular dynamics simulation unveils the conformational flexibility of the interdomain linker in the bacterial transcriptional regulator GabR from Bacillus subtilis bound to pyridoxal 5’-phosphate
GabR from Bacillus subtilis is a transcriptional regulator belonging to the MocR subfamily of the GntR regulators. The structure of the MocR regulators is characterized by the presence of two domains: i) a N-terminal domain, about 60 residue long, possessing the winged-Helix-Turn-Helix (wHTH) archit...
Autores principales: | Milano, Teresa, Gulzar, Adnan, Narzi, Daniele, Guidoni, Leonardo, Pascarella, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734734/ https://www.ncbi.nlm.nih.gov/pubmed/29253008 http://dx.doi.org/10.1371/journal.pone.0189270 |
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