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Identification of ᴅ-amino acid-containing peptides in human serum

Biologically uncommon d-aspartate (d-Asp) residues have been shown to accumulate in proteins associated with age-related human disorders, such as cataract and Alzheimer disease. Such d-Asp-containing proteins are unlikely to be broken down completely because metabolic enzymes recognize only proteins...

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Detalles Bibliográficos
Autores principales: Ha, Seongmin, Kim, Ingu, Takata, Takumi, Kinouchi, Tadatoshi, Isoyama, Masaharu, Suzuki, Minoru, Fujii, Noriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734745/
https://www.ncbi.nlm.nih.gov/pubmed/29253022
http://dx.doi.org/10.1371/journal.pone.0189972