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Identification of ᴅ-amino acid-containing peptides in human serum
Biologically uncommon d-aspartate (d-Asp) residues have been shown to accumulate in proteins associated with age-related human disorders, such as cataract and Alzheimer disease. Such d-Asp-containing proteins are unlikely to be broken down completely because metabolic enzymes recognize only proteins...
Autores principales: | Ha, Seongmin, Kim, Ingu, Takata, Takumi, Kinouchi, Tadatoshi, Isoyama, Masaharu, Suzuki, Minoru, Fujii, Noriko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734745/ https://www.ncbi.nlm.nih.gov/pubmed/29253022 http://dx.doi.org/10.1371/journal.pone.0189972 |
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