Crystal structures of H-2D(b) in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity

Post-translational modifications significantly broaden the epitope repertoire for major histocompatibility class I complexes (MHC-I) and may allow viruses to escape immune recognition. Lymphocytic choriomeningitis virus (LCMV) infection of H-2(b) mice generates CD8(+) CTL responses directed towards...

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Detalles Bibliográficos
Autores principales: Hafstrand, Ida, Badia-Martinez, Daniel, Josey, Benjamin John, Norström, Melissa, Buratto, Jérémie, Pellegrino, Sara, Duru, Adil Doganay, Sandalova, Tatyana, Achour, Adnane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734757/
https://www.ncbi.nlm.nih.gov/pubmed/29253009
http://dx.doi.org/10.1371/journal.pone.0189584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734757/
https://www.ncbi.nlm.nih.gov/pubmed/29253009
http://dx.doi.org/10.1371/journal.pone.0189584

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