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Crystal structures of H-2D(b) in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity
Post-translational modifications significantly broaden the epitope repertoire for major histocompatibility class I complexes (MHC-I) and may allow viruses to escape immune recognition. Lymphocytic choriomeningitis virus (LCMV) infection of H-2(b) mice generates CD8(+) CTL responses directed towards...
Autores principales: | Hafstrand, Ida, Badia-Martinez, Daniel, Josey, Benjamin John, Norström, Melissa, Buratto, Jérémie, Pellegrino, Sara, Duru, Adil Doganay, Sandalova, Tatyana, Achour, Adnane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734757/ https://www.ncbi.nlm.nih.gov/pubmed/29253009 http://dx.doi.org/10.1371/journal.pone.0189584 |
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