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Characterization of CobB kinetics and inhibition by nicotinamide
Lysine acetylation has emerged as a global protein regulation system in all domains of life. Sirtuins, or Sir2-like enzymes, are a family of histone deacetylases characterized by their employing NAD(+) as a co-substrate. Sirtuins can deacetylate several acetylated proteins, but a consensus substrate...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734772/ https://www.ncbi.nlm.nih.gov/pubmed/29253849 http://dx.doi.org/10.1371/journal.pone.0189689 |