Downregulation of monocytic differentiation via modulation of CD147 by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors

CD147 is an activation induced glycoprotein that promotes the secretion and activation of matrix metalloproteinases (MMPs) and is upregulated during the differentiation of macrophages. Interestingly, some of the molecular functions of CD147 rely on its glycosylation status: the highly glycosylated f...

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Detalles Bibliográficos
Autores principales: Sasidhar, Manda V., Chevooru, Sai Krishnaveni, Eickelberg, Oliver, Hartung, Hans-Peter, Neuhaus, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734787/
https://www.ncbi.nlm.nih.gov/pubmed/29253870
http://dx.doi.org/10.1371/journal.pone.0189701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734787/
https://www.ncbi.nlm.nih.gov/pubmed/29253870
http://dx.doi.org/10.1371/journal.pone.0189701

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