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Free-living human cells reconfigure their chromosomes in the evolution back to uni-cellularity

Cells of multi-cellular organisms evolve toward uni-cellularity in the form of cancer and, if humans intervene, continue to evolve in cell culture. During this process, gene dosage relationships may evolve in novel ways to cope with the new environment and may regress back to the ancestral uni-cellu...

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Detalles Bibliográficos
Autores principales: Xu, Jin, Peng, Xinxin, Chen, Yuxin, Zhang, Yuezheng, Ma, Qin, Liang, Liang, Carter, Ava C, Lu, Xuemei, Wu, Chung-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734875/
https://www.ncbi.nlm.nih.gov/pubmed/29251591
http://dx.doi.org/10.7554/eLife.28070