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The role of microglia and their CX3CR1 signaling in adult neurogenesis in the olfactory bulb

Microglia play important roles in perinatal neuro- and synapto-genesis. To test the role of microglia in these processes during adulthood, we examined the effects of microglia depletion, via treatment of mice with the CSF-1 receptor antagonist PLX5622, and abrogated neuronal-microglial communication...

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Detalles Bibliográficos
Autores principales: Reshef, Ronen, Kudryavitskaya, Elena, Shani-Narkiss, Haran, Isaacson, Batya, Rimmerman, Neta, Mizrahi, Adi, Yirmiya, Raz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734876/
https://www.ncbi.nlm.nih.gov/pubmed/29251592
http://dx.doi.org/10.7554/eLife.30809