Novel inhibitors targeting Venezuelan equine encephalitis virus capsid protein identified using In Silico Structure-Based-Drug-Design

Therapeutics are currently unavailable for Venezuelan equine encephalitis virus (VEEV), which elicits flu-like symptoms and encephalitis in humans, with an estimated 14% of cases resulting in neurological disease. Here we identify anti-VEEV agents using in silico structure-based-drug-design (SBDD) f...

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Detalles Bibliográficos
Autores principales: Shechter, Sharon, Thomas, David R., Lundberg, Lindsay, Pinkham, Chelsea, Lin, Shih-Chao, Wagstaff, Kylie M., Debono, Aaron, Kehn-Hall, Kylene, Jans, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735092/
https://www.ncbi.nlm.nih.gov/pubmed/29255256
http://dx.doi.org/10.1038/s41598-017-17672-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735092/
https://www.ncbi.nlm.nih.gov/pubmed/29255256
http://dx.doi.org/10.1038/s41598-017-17672-9

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