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Mechanically stable solvent-free lipid bilayers in nano- and micro-tapered apertures for reconstitution of cell-free synthesized hERG channels

The self-assembled bilayer lipid membrane (BLM) is the basic component of the cell membrane. The reconstitution of ion channel proteins in artificially formed BLMs represents a well-defined system for the functional analysis of ion channels and screening the effects of drugs that act on them. Howeve...

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Detalles Bibliográficos
Autores principales: Tadaki, Daisuke, Yamaura, Daichi, Araki, Shun, Yoshida, Miyu, Arata, Kohei, Ohori, Takeshi, Ishibashi, Ken-ichi, Kato, Miki, Ma, Teng, Miyata, Ryusuke, Tozawa, Yuzuru, Yamamoto, Hideaki, Niwano, Michio, Hirano-Iwata, Ayumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735097/
https://www.ncbi.nlm.nih.gov/pubmed/29255199
http://dx.doi.org/10.1038/s41598-017-17905-x