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Mechanically stable solvent-free lipid bilayers in nano- and micro-tapered apertures for reconstitution of cell-free synthesized hERG channels
The self-assembled bilayer lipid membrane (BLM) is the basic component of the cell membrane. The reconstitution of ion channel proteins in artificially formed BLMs represents a well-defined system for the functional analysis of ion channels and screening the effects of drugs that act on them. Howeve...
Autores principales: | Tadaki, Daisuke, Yamaura, Daichi, Araki, Shun, Yoshida, Miyu, Arata, Kohei, Ohori, Takeshi, Ishibashi, Ken-ichi, Kato, Miki, Ma, Teng, Miyata, Ryusuke, Tozawa, Yuzuru, Yamamoto, Hideaki, Niwano, Michio, Hirano-Iwata, Ayumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735097/ https://www.ncbi.nlm.nih.gov/pubmed/29255199 http://dx.doi.org/10.1038/s41598-017-17905-x |
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