Vemurafenib Limits Influenza A Virus Propagation by Targeting Multiple Signaling Pathways

Influenza A viruses (IAV) can cause severe global pandemic outbreaks. The currently licensed antiviral drugs are not very effective and prone to viral resistance. Thus, novel effective and broadly active drugs are urgently needed. We have identified the cellular Raf/MEK/ERK signaling cascade as cruc...

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Detalles Bibliográficos
Autores principales: Holzberg, Magdalena, Boergeling, Yvonne, Schräder, Tobias, Ludwig, Stephan, Ehrhardt, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735105/
https://www.ncbi.nlm.nih.gov/pubmed/29312159
http://dx.doi.org/10.3389/fmicb.2017.02426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735105/
https://www.ncbi.nlm.nih.gov/pubmed/29312159
http://dx.doi.org/10.3389/fmicb.2017.02426

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