Curcumin activates DNA repair pathway in bone marrow to improve carboplatin-induced myelosuppression

Carboplatin, a second-generation platinum agent, has been used as a cancer therapy for decades and exhibits strong anti-tumor activity. However, the wide application of carboplatin is largely limited due to its side effects, especially myelosuppression. Here, we combined carboplatin with curcumin, a...

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Detalles Bibliográficos
Autores principales: Chen, Xiao, Wang, Jigang, Fu, Zhongping, Zhu, Bo, Wang, Jie, Guan, Shengwen, Hua, Zichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735145/
https://www.ncbi.nlm.nih.gov/pubmed/29255221
http://dx.doi.org/10.1038/s41598-017-16436-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735145/
https://www.ncbi.nlm.nih.gov/pubmed/29255221
http://dx.doi.org/10.1038/s41598-017-16436-9

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