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Curcumin activates DNA repair pathway in bone marrow to improve carboplatin-induced myelosuppression
Carboplatin, a second-generation platinum agent, has been used as a cancer therapy for decades and exhibits strong anti-tumor activity. However, the wide application of carboplatin is largely limited due to its side effects, especially myelosuppression. Here, we combined carboplatin with curcumin, a...
Autores principales: | Chen, Xiao, Wang, Jigang, Fu, Zhongping, Zhu, Bo, Wang, Jie, Guan, Shengwen, Hua, Zichun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735145/ https://www.ncbi.nlm.nih.gov/pubmed/29255221 http://dx.doi.org/10.1038/s41598-017-16436-9 |
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