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A flexible ontology for inference of emergent whole cell function from relationships between subcellular processes

Whole cell responses arise from coordinated interactions between diverse human gene products functioning within various pathways underlying sub-cellular processes (SCP). Lower level SCPs interact to form higher level SCPs, often in a context specific manner to give rise to whole cell function. We so...

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Detalles Bibliográficos
Autores principales: Hansen, Jens, Meretzky, David, Woldesenbet, Simeneh, Stolovitzky, Gustavo, Iyengar, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735158/
https://www.ncbi.nlm.nih.gov/pubmed/29255142
http://dx.doi.org/10.1038/s41598-017-16627-4