Entropy and Polarity Control the Partition and Transportation of Drug-like Molecules in Biological Membrane

Partition and transportation of drug in the plasma membrane of a mammalian cell are the prerequisite for its function on target protein. Therefore, comprehensive understanding of the physicochemical properties and mechanism behind these complex phenomena is crucial in pharmaceutical research. By usi...

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Detalles Bibliográficos
Autores principales: Zhu, Qiang, Lu, Yilin, He, Xibing, Liu, Tao, Chen, Hongwei, Wang, Fang, Zheng, Dong, Dong, Hao, Ma, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735159/
https://www.ncbi.nlm.nih.gov/pubmed/29255188
http://dx.doi.org/10.1038/s41598-017-18012-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735159/
https://www.ncbi.nlm.nih.gov/pubmed/29255188
http://dx.doi.org/10.1038/s41598-017-18012-7

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