Hormonal Contraceptives Differentially Suppress TFV and TAF Inhibition of HIV Infection and TFV-DP in Blood and Genital Tract CD4+ T cells

HIV prevention research is focused on combining antiretrovirals (ARV) and progestin contraceptives to prevent HIV infection and pregnancy. The possibility that progestins compromise ARV anti-HIV activity prompted us to evaluate the effects of progestins on tenofovir (TFV) and TFV-alafenamide (TAF) o...

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Detalles Bibliográficos
Autores principales: Shen, Zheng, Rodriguez-Garcia, Marta, Patel, Mickey V., Bodwell, Jack, Kashuba, Angela D. M., Wira, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735186/
https://www.ncbi.nlm.nih.gov/pubmed/29255206
http://dx.doi.org/10.1038/s41598-017-18078-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735186/
https://www.ncbi.nlm.nih.gov/pubmed/29255206
http://dx.doi.org/10.1038/s41598-017-18078-3

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