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Hormonal Contraceptives Differentially Suppress TFV and TAF Inhibition of HIV Infection and TFV-DP in Blood and Genital Tract CD4+ T cells
HIV prevention research is focused on combining antiretrovirals (ARV) and progestin contraceptives to prevent HIV infection and pregnancy. The possibility that progestins compromise ARV anti-HIV activity prompted us to evaluate the effects of progestins on tenofovir (TFV) and TFV-alafenamide (TAF) o...
Autores principales: | Shen, Zheng, Rodriguez-Garcia, Marta, Patel, Mickey V., Bodwell, Jack, Kashuba, Angela D. M., Wira, Charles R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735186/ https://www.ncbi.nlm.nih.gov/pubmed/29255206 http://dx.doi.org/10.1038/s41598-017-18078-3 |
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