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Runx3 plays a critical role in restriction-point and defense against cellular transformation

The restriction (R)-point decision is fundamental to normal differentiation and the G(1)–S transition, and the decision-making machinery is perturbed in nearly all cancer cells. The mechanisms underlying the cellular context–dependent R-point decision remain poorly understood. We found that the R-po...

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Detalles Bibliográficos
Autores principales: Chi, X-Z, Lee, J-W, Lee, Y-S, Park, I Y, Ito, Y, Bae, S-C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735299/
https://www.ncbi.nlm.nih.gov/pubmed/28846108
http://dx.doi.org/10.1038/onc.2017.290