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Runx3 plays a critical role in restriction-point and defense against cellular transformation
The restriction (R)-point decision is fundamental to normal differentiation and the G(1)–S transition, and the decision-making machinery is perturbed in nearly all cancer cells. The mechanisms underlying the cellular context–dependent R-point decision remain poorly understood. We found that the R-po...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735299/ https://www.ncbi.nlm.nih.gov/pubmed/28846108 http://dx.doi.org/10.1038/onc.2017.290 |