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Berberine binds RXRα to suppress β-catenin signaling in colon cancer cells

Berberine, an isoquinoline alkaloid, is a traditional oriental medicine used to treat diarrhea and gastroenteritis. Recently, we reported that it could inhibit the growth of intestinal polyp in animals and in patients with the familial adenomatous polyposis by downregulating β-catenin signaling. How...

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Detalles Bibliográficos
Autores principales: Ruan, H, Zhan, Y Y, Hou, J, Xu, B, Chen, B, Tian, Y, Wu, D, Zhao, Y, Zhang, Y, Chen, X, Mi, P, Zhang, L, Zhang, S, Wang, X, Cao, H, Zhang, W, Wang, H, Li, H, Su, Y, Zhang, X K, Hu, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735301/
https://www.ncbi.nlm.nih.gov/pubmed/28846104
http://dx.doi.org/10.1038/onc.2017.296