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The novel organic mononitrate NDHP attenuates hypertension and endothelial dysfunction in hypertensive rats
RATIONALE: Development and progression of cardiovascular diseases, including hypertension, are often associated with impaired nitric oxide synthase (NOS) function and nitric oxide (NO) deficiency. Current treatment strategies to restore NO bioavailability with organic nitrates are hampered by undesi...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735329/ https://www.ncbi.nlm.nih.gov/pubmed/29268201 http://dx.doi.org/10.1016/j.redox.2017.12.004 |