Cargando…

The novel organic mononitrate NDHP attenuates hypertension and endothelial dysfunction in hypertensive rats

RATIONALE: Development and progression of cardiovascular diseases, including hypertension, are often associated with impaired nitric oxide synthase (NOS) function and nitric oxide (NO) deficiency. Current treatment strategies to restore NO bioavailability with organic nitrates are hampered by undesi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Paulo, Luciano L., Cruz, Josiane Campos, Zhuge, Zhengbing, Carvalho-Galvão, Alynne, Brandão, Maria C.R., Diniz, Thiago F., Haworth, Sarah McCann, Athayde-Filho, Petrônio F., Lemos, Virginia S., Lundberg, Jon O., Montenegro, Marcelo F., Braga, Valdir A., Carlström, Mattias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735329/ https://www.ncbi.nlm.nih.gov/pubmed/29268201 http://dx.doi.org/10.1016/j.redox.2017.12.004

Ejemplares similares

Synthesis and characterization of a novel organic nitrate NDHP: Role of xanthine oxidoreductase-mediated nitric oxide formation
por: Zhuge, Zhengbing, et al.
Publicado: (2017)

Central Inhibition of Tumor Necrosis Factor Alpha Reduces Hypertension by Attenuating Oxidative Stress in the Rostral Ventrolateral Medulla in Renovascular Hypertensive Rats
por: Carvalho-Galvão, Alynne, et al.
Publicado: (2019)

AMP-activated protein kinase activation and NADPH oxidase inhibition by inorganic nitrate and nitrite prevent liver steatosis
por: Cordero-Herrera, Isabel, et al.
Publicado: (2019)

Rutin reduces oxidative stress in animals with renovascular hypertension
por: Duarte, Rayssa, et al.
Publicado: (2014)

Red blood cells from endothelial nitric oxide synthase-deficient mice induce vascular dysfunction involving oxidative stress and endothelial arginase I
por: Zhuge, Zhengbing, et al.
Publicado: (2023)

A Newly Isolated Carboxymethyl-Glucan (CM-G) Restores Depressed Baroreflex Sensitivity in Renovascular Hypertensive Rats
por: Carvalho-Galvão, Alynne, et al.
Publicado: (2018)

Renal denervation attenuates hypertension and renal dysfunction in a model of cardiovascular and renal disease, which is associated with reduced NADPH and xanthine oxidase activity
por: Peleli, Maria, et al.
Publicado: (2017)

MON-217 Maternal Androgen Excess and Obesity Induce Cardiac Hypertrophy and Left Ventricular Dysfunction in Female Offspring
por: Manti, Maria, et al.
Publicado: (2019)

Amorphization of Thiamine Mononitrate: A Study of Crystallization Inhibition and Chemical Stability of Thiamine in Thiamine Mononitrate Amorphous Solid Dispersions
por: Arioglu-Tuncil, Seda, et al.
Publicado: (2020)

The 5 kDa Protein NdhP Is Essential for Stable NDH-1L Assembly in Thermosynechococcus elongatus
por: Wulfhorst, Hannes, et al.
Publicado: (2014)

NO-ferroheme is a signaling entity in the vasculature
por: Kleschyov, Andrei L., et al.
Publicado: (2023)

The new nitric oxide donor cyclohexane nitrate induces vasorelaxation, hypotension, and antihypertensive effects via NO/cGMP/PKG pathway
por: Mendes-Júnior, Leônidas das G., et al.
Publicado: (2015)

Isosorbide mononitrate promotes angiogenesis in embryonic development of zebrafish
por: Lv, Hui, et al.
Publicado: (2020)

Management of Massive Rivaroxaban Overdose With Acetaminophen and Isosorbide Mononitrate Overdose
por: Casey, Bradley, et al.
Publicado: (2023)

Formulation and evaluation of polyelectrolyte complex-based matrix tablet of Isosorbide Mononitrate
por: Syed, Iizhar Ahmed, et al.
Publicado: (2014)

Inorganic nitrate and nitrite ameliorate kidney fibrosis by restoring lipid metabolism via dual regulation of AMP-activated protein kinase and the AKT-PGC1α pathway
por: Li, Xuechen, et al.
Publicado: (2022)

Dietary nitrate attenuates high-fat diet-induced obesity via mechanisms involving higher adipocyte respiration and alterations in inflammatory status
por: Peleli, M., et al.
Publicado: (2019)

Genetic Abrogation of Adenosine A(3) Receptor Prevents Uninephrectomy and High Salt–Induced Hypertension
por: Yang, Ting, et al.
Publicado: (2016)

Clinical study of isosorbide mononitrate treatment for angina pectoris in coronary heart disease
por: TAN, ZHENG, et al.
Publicado: (2013)

Primary Pulmonary Hypertension
por: Haworth, Sheila G
Publicado: (1998)

The management of pulmonary hypertension in children
por: Haworth, S G
Publicado: (2008)

Vascular Dysfunction in Experimental Diabetes Is Improved by Pentaerithrityl Tetranitrate but Not Isosorbide-5-Mononitrate Therapy
por: Schuhmacher, Swenja, et al.
Publicado: (2011)

Evaluation of Isosorbide Mononitrate for Preinduction of Cervical Ripening: A Randomized Placebo-Controlled Trial
por: Krishnamurthy, Ramya, et al.
Publicado: (2015)

Effects of Cilostazol and Isosorbide Mononitrate on Cerebral Hemodynamics in the LACI-1 Randomized Controlled Trial
por: Blair, Gordon W., et al.
Publicado: (2021)

Chemically Cross-Linked Poly(acrylic-co-vinylsulfonic) Acid Hydrogel for the Delivery of Isosorbide Mononitrate
por: Hussain, Talib, et al.
Publicado: (2013)

Formulation and In Vitro Characterization of Xanthan Gum-Based Sustained Release Matrix Tables of Isosorbide-5- Mononitrate
por: Kar, Rajat, et al.
Publicado: (2010)

Vericiguat in combination with isosorbide mononitrate in patients with chronic coronary syndromes: The randomized, phase Ib, VISOR study
por: Boettcher, Michael, et al.
Publicado: (2022)

The Influence of Ixeris sonchifolia Hance Injection Combined with Isosorbide Mononitrate in Patients with Coronary Heart Disease and Diabetes
por: Zhang, Li, et al.
Publicado: (2022)

Synergetic delivery of artesunate and isosorbide 5-mononitrate with reduction-sensitive polymer nanoparticles for ovarian cancer chemotherapy
por: Li, Guang, et al.
Publicado: (2022)

A Disintegrin and Metalloprotease 17 in the Cardiovascular and Central Nervous Systems
por: Xu, Jiaxi, et al.
Publicado: (2016)

Coconut oil supplementation reduces blood pressure and oxidative stress in spontaneously hypertensive rats
por: Bandeira Alves, Naiane Ferraz, et al.
Publicado: (2014)

Renovascular effects of inorganic nitrate following ischemia-reperfusion of the kidney
por: Zhang, Gensheng, et al.
Publicado: (2020)

Randomized Comparison of Isosorbide Mononitrate and PGE2 Gel for Cervical Ripening at Term including High Risk Pregnancy
por: Agarwal, Kavita, et al.
Publicado: (2014)

The Relationship between Compound Danshen Dripping Pills with Isosorbide Mononitrate in the Treatment of Elderly Patients with Unstable Angina Pectoris
por: Liang, Yulin, et al.
Publicado: (2018)

Effects of isosorbide mononitrate loaded nanoparticles conjugated with anti-Staphylococcus aureus α-toxin on Staphylococcus aureus biofilms
por: Zhang, Yaqian, et al.
Publicado: (2020)

Effect of pH and concentration on the chemical stability and reaction kinetics of thiamine mononitrate and thiamine chloride hydrochloride in solution
por: Voelker, Adrienne L., et al.
Publicado: (2021)

α-Lipoic Acid Reduces Hypertension and Increases Baroreflex Sensitivity in Renovascular Hypertensive Rats
por: Queiroz, Thyago M., et al.
Publicado: (2012)

Nitric oxide-induced headache may arise from extracerebral arteries as judged from tolerance to isosorbide-5-mononitrate
por: Christiansen, Ingelise, et al.
Publicado: (2008)

2-(5-Methyl-1,3,4-oxadiazol-2-yl)phenyl acetate
por: dos Santos, Alexsandro F., et al.
Publicado: (2014)

Quercetin Improves Baroreflex Sensitivity in Spontaneously Hypertensive Rats
por: Monteiro, Matheus M. O., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_rinkopo7q47af7r2mulgqb46ol