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Evaluation of in vitro and in vivo anticancer potential of two 5-acetamido chalcones against breast cancer

Two 5'acetamido chalcones, C1 and C2 were synthesized by Claisen-Schmidt condensation method and characterized by IR, LC-MS, (1)H NMR and (13)C NMR. These compounds were evaluated for anticancer activity in vitro in breast cancer cell lines (MCF-7 and MDA-MB-231) using MTT assay, anti-metastati...

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Detalles Bibliográficos
Autores principales: Wankhede, Sonal, Kumar, Nitesh, Simon, Lalitha, Biswas, Subhankar, Gourishetti, Karthik, Ramalingayya, Grandhi Venkata, Joshi, Mit, Rao, C. Mallikarjuna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735347/
https://www.ncbi.nlm.nih.gov/pubmed/29285012
http://dx.doi.org/10.17179/excli2017-624