Dexmedetomidine Protects Cardiomyocytes against Hypoxia/Reoxygenation Injury by Suppressing TLR4-MyD88-NF-κB Signaling

OBJECTIVE: We previously reported that dexmedetomidine (DEX) offers cardioprotection against ischemia/reperfusion injury in rats. Here, we evaluated the role of toll-like receptors 4- (TLR4-) myeloid differentiation primary response 88- (MyD88-) nuclear factor-kappa B (NF-κB) signaling in DEX-mediat...

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Detalles Bibliográficos
Autores principales: Gao, Jin-meng, Meng, Xiao-wen, Zhang, Juan, Chen, Wei-rong, Xia, Fan, Peng, Ke, Ji, Fu-hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735617/
https://www.ncbi.nlm.nih.gov/pubmed/29359143
http://dx.doi.org/10.1155/2017/1674613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735617/
https://www.ncbi.nlm.nih.gov/pubmed/29359143
http://dx.doi.org/10.1155/2017/1674613

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