Melanoma cells replicate through chemotherapy by reducing levels of key homologous recombination protein RAD51 and increasing expression of translesion synthesis DNA polymerase ζ

BACKGROUND: The global incidence of melanoma has been increasing faster than any other form of cancer. New therapies offer exciting prospects for improved survival, but the development of resistance is a major problem and there remains a need for additional effective melanoma therapy. Platinum compo...

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Detalles Bibliográficos
Autores principales: Song, Liang, McNeil, Ewan M., Ritchie, Ann-Marie, Astell, Katy R., Gourley, Charlie, Melton, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735618/
https://www.ncbi.nlm.nih.gov/pubmed/29254481
http://dx.doi.org/10.1186/s12885-017-3864-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735618/
https://www.ncbi.nlm.nih.gov/pubmed/29254481
http://dx.doi.org/10.1186/s12885-017-3864-6

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