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Sustained Activity of Metabotropic Glutamate Receptor: Homer, Arrestin, and Beyond
When activated, metabotropic glutamate receptors (mGlus) exert long-lasting changes within the glutamatergic synapses. One mechanism is a tonic effect of downstream signal transduction pathways via sustained activation of mGlu itself. Like many other G protein-coupled receptors (GPCRs), mGlu can exi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735635/ https://www.ncbi.nlm.nih.gov/pubmed/29359050 http://dx.doi.org/10.1155/2017/5125624 |