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Sustained Activity of Metabotropic Glutamate Receptor: Homer, Arrestin, and Beyond

When activated, metabotropic glutamate receptors (mGlus) exert long-lasting changes within the glutamatergic synapses. One mechanism is a tonic effect of downstream signal transduction pathways via sustained activation of mGlu itself. Like many other G protein-coupled receptors (GPCRs), mGlu can exi...

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Detalles Bibliográficos
Autores principales: Chung, Geehoon, Kim, Sang Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735635/
https://www.ncbi.nlm.nih.gov/pubmed/29359050
http://dx.doi.org/10.1155/2017/5125624