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The Significance of Hypothiocyanite Production via the Pendrin/DUOX/Peroxidase Pathway in the Pathogenesis of Asthma

Inhaled corticosteroids (ICSs) are used as first-line drugs for asthma, and various novel antiasthma drugs targeting type 2 immune mediators are now under development. However, molecularly targeted drugs are expensive, creating an economic burden on patients. We and others previously found pendrin/S...

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Detalles Bibliográficos
Autores principales: Izuhara, Kenji, Suzuki, Shoichi, Ogawa, Masahiro, Nunomura, Satoshi, Nanri, Yasuhiro, Mitamura, Yasutaka, Yoshihara, Tomohito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735670/
https://www.ncbi.nlm.nih.gov/pubmed/29359006
http://dx.doi.org/10.1155/2017/1054801