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Moloney leukemia virus 10 (MOV10) inhibits the degradation of APOBEC3G through interference with the Vif-mediated ubiquitin–proteasome pathway

BACKGROUND: MOV10 protein has ATP-dependent 5′–3′ RNA helicase activity and belongs to the UPF1p superfamily. It can inhibit human immunodeficiency virus type 1 (HIV-1) replication at multiple stages and interact with apolipoprotein-B-mRNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G or A3...

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Detalles Bibliográficos
Autores principales: Chen, Cancan, Ma, Xiaocao, Hu, Qifei, Li, Xinghua, Huang, Feng, Zhang, Junsong, Pan, Ting, Xia, Jinyu, Liu, Chao, Zhang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735797/
https://www.ncbi.nlm.nih.gov/pubmed/29258557
http://dx.doi.org/10.1186/s12977-017-0382-1