Predictive model identifies strategies to enhance TSP1-mediated apoptosis signaling

BACKGROUND: Thrombospondin-1 (TSP1) is a matricellular protein that functions to inhibit angiogenesis. An important pathway that contributes to this inhibitory effect is triggered by TSP1 binding to the CD36 receptor, inducing endothelial cell apoptosis. However, therapies that mimic this function h...

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Detalles Bibliográficos
Autores principales: Wu, Qianhui, Finley, Stacey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735807/
https://www.ncbi.nlm.nih.gov/pubmed/29258506
http://dx.doi.org/10.1186/s12964-017-0207-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735807/
https://www.ncbi.nlm.nih.gov/pubmed/29258506
http://dx.doi.org/10.1186/s12964-017-0207-9

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