Cargando…
Predictive model identifies strategies to enhance TSP1-mediated apoptosis signaling
BACKGROUND: Thrombospondin-1 (TSP1) is a matricellular protein that functions to inhibit angiogenesis. An important pathway that contributes to this inhibitory effect is triggered by TSP1 binding to the CD36 receptor, inducing endothelial cell apoptosis. However, therapies that mimic this function h...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735807/ https://www.ncbi.nlm.nih.gov/pubmed/29258506 http://dx.doi.org/10.1186/s12964-017-0207-9 |