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What is the evidence that tau pathology spreads through prion-like propagation?

Emerging experimental evidence suggests that the spread of tau pathology in the brain in Tauopathies reflects the propagation of abnormal tau species along neuroanatomically connected brain areas. This propagation could occur through a “prion-like” mechanism involving transfer of abnormal tau seeds...

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Detalles Bibliográficos
Autores principales: Mudher, Amrit, Colin, Morvane, Dujardin, Simon, Medina, Miguel, Dewachter, Ilse, Naini, Seyedeh Maryam Alavi, Mandelkow, Eva-Maria, Mandelkow, Eckhard, Buée, Luc, Goedert, Michel, Brion, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735872/
https://www.ncbi.nlm.nih.gov/pubmed/29258615
http://dx.doi.org/10.1186/s40478-017-0488-7