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Mesenchymal stem cell conditioned medium alleviates oxidative stress injury induced by hydrogen peroxide via regulating miR143 and its target protein in hepatocytes

BACKGROUND: To investigate the impact of miRNA (microRNA) on hepatic oxidative stress damage under the human mesenchymal stem cell conditioned medium (MSC-CM) and explore the roles of the beta-1 adrenergic receptor (ADRB1) and hexokinase 2 (HK2) in this process. METHODS: Hydrogen peroxide was used t...

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Detalles Bibliográficos
Autores principales: Xu, Xuejing, Li, Dong, Li, Xue, Shi, Qing, Ju, Xiuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735881/
https://www.ncbi.nlm.nih.gov/pubmed/29258429
http://dx.doi.org/10.1186/s12865-017-0232-x