Low-dose strontium stimulates osteogenesis but high-dose doses cause apoptosis in human adipose-derived stem cells via regulation of the ERK1/2 signaling pathway

BACKGROUND: Strontium is a widely used anti-osteoporotic agent due to its dual effects on inhibiting bone resorption and stimulating bone formation. Thus, we studied the dose response of strontium on osteo-inductive efficiency in human adipose-derived stem cells (hASCs). METHOD: Qualitative alkaline...

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Detalles Bibliográficos
Autores principales: Aimaiti, Abudousaimi, Maimaitiyiming, Asihaerjiang, Boyong, Xu, Aji, Kaisaier, Li, Cao, Cui, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735894/
https://www.ncbi.nlm.nih.gov/pubmed/29254499
http://dx.doi.org/10.1186/s13287-017-0726-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735894/
https://www.ncbi.nlm.nih.gov/pubmed/29254499
http://dx.doi.org/10.1186/s13287-017-0726-8

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