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Low-dose strontium stimulates osteogenesis but high-dose doses cause apoptosis in human adipose-derived stem cells via regulation of the ERK1/2 signaling pathway

BACKGROUND: Strontium is a widely used anti-osteoporotic agent due to its dual effects on inhibiting bone resorption and stimulating bone formation. Thus, we studied the dose response of strontium on osteo-inductive efficiency in human adipose-derived stem cells (hASCs). METHOD: Qualitative alkaline...

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Detalles Bibliográficos
Autores principales:	Aimaiti, Abudousaimi, Maimaitiyiming, Asihaerjiang, Boyong, Xu, Aji, Kaisaier, Li, Cao, Cui, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735894/ https://www.ncbi.nlm.nih.gov/pubmed/29254499 http://dx.doi.org/10.1186/s13287-017-0726-8

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