PAK6 Phosphorylates 14-3-3γ to Regulate Steady State Phosphorylation of LRRK2

Mutations in Leucine-rich repeat kinase 2 (LRRK2) are associated with Parkinson's disease (PD) and, as such, LRRK2 is considered a promising therapeutic target for age-related neurodegeneration. Although the cellular functions of LRRK2 in health and disease are incompletely understood, robust e...

Descripción completa

Detalles Bibliográficos
Autores principales: Civiero, Laura, Cogo, Susanna, Kiekens, Anneleen, Morganti, Claudia, Tessari, Isabella, Lobbestael, Evy, Baekelandt, Veerle, Taymans, Jean-Marc, Chartier-Harlin, Marie-Christine, Franchin, Cinzia, Arrigoni, Giorgio, Lewis, Patrick A., Piccoli, Giovanni, Bubacco, Luigi, Cookson, Mark R., Pinton, Paolo, Greggio, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735978/
https://www.ncbi.nlm.nih.gov/pubmed/29311810
http://dx.doi.org/10.3389/fnmol.2017.00417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735978/
https://www.ncbi.nlm.nih.gov/pubmed/29311810
http://dx.doi.org/10.3389/fnmol.2017.00417

Ejemplares similares