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Protein phosphatase 2Cδ/Wip1 regulates phospho-p90RSK2 activity in lesional psoriatic skin

OBJECTIVES: P90 ribosomal S6 kinase (RSK) 1 and 2 are serine/threonine protein kinases believed to mediate proliferation and apoptosis via the extracellular signal-regulated kinases (ERK1/2) signaling pathway. Macrophage migration inhibitory factor (MIF) and epidermal growth factor (EGF) are activat...

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Detalles Bibliográficos
Autores principales: Rasmussen, Mads K, Nielsen, Jakob, Kjellerup, Rasmus B, Andersen, Stine M, Rittig, Anne H, Johansen, Claus, Iversen, Lars, Gesser, Borbala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735993/
https://www.ncbi.nlm.nih.gov/pubmed/29290690
http://dx.doi.org/10.2147/JIR.S152869