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Protein phosphatase 2Cδ/Wip1 regulates phospho-p90RSK2 activity in lesional psoriatic skin
OBJECTIVES: P90 ribosomal S6 kinase (RSK) 1 and 2 are serine/threonine protein kinases believed to mediate proliferation and apoptosis via the extracellular signal-regulated kinases (ERK1/2) signaling pathway. Macrophage migration inhibitory factor (MIF) and epidermal growth factor (EGF) are activat...
Autores principales: | Rasmussen, Mads K, Nielsen, Jakob, Kjellerup, Rasmus B, Andersen, Stine M, Rittig, Anne H, Johansen, Claus, Iversen, Lars, Gesser, Borbala |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735993/ https://www.ncbi.nlm.nih.gov/pubmed/29290690 http://dx.doi.org/10.2147/JIR.S152869 |
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