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Metabolic Profiling of Adiponectin Levels in Adults: Mendelian Randomization Analysis

BACKGROUND—: Adiponectin, a circulating adipocyte-derived protein, has insulin-sensitizing, anti-inflammatory, antiatherogenic, and cardiomyocyte-protective properties in animal models. However, the systemic effects of adiponectin in humans are unknown. Our aims were to define the metabolic profile...

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Detalles Bibliográficos
Autores principales: Borges, Maria Carolina, Barros, Aluísio J.D., Ferreira, Diana L. Santos, Casas, Juan Pablo, Horta, Bernardo Lessa, Kivimaki, Mika, Kumari, Meena, Menon, Usha, Gaunt, Tom R., Ben-Shlomo, Yoav, Freitas, Deise F., Oliveira, Isabel O., Gentry-Maharaj, Aleksandra, Fourkala, Evangelia, Lawlor, Debbie A., Hingorani, Aroon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736126/
https://www.ncbi.nlm.nih.gov/pubmed/29237687
http://dx.doi.org/10.1161/CIRCGENETICS.117.001837