Influence of an immunodominant herpes simplex virus type 1 CD8(+) T cell epitope on the target hierarchy and function of subdominant CD8(+) T cells

Herpes simplex virus type 1 (HSV-1) latency in sensory ganglia such as trigeminal ganglia (TG) is associated with a persistent immune infiltrate that includes effector memory CD8(+) T cells that can influence HSV-1 reactivation. In C57BL/6 mice, HSV-1 induces a highly skewed CD8(+) T cell repertoire...

Descripción completa

Detalles Bibliográficos
Autores principales: Treat, Benjamin R., Bidula, Sarah M., Ramachandran, Srividya, St Leger, Anthony J., Hendricks, Robert L., Kinchington, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736228/
https://www.ncbi.nlm.nih.gov/pubmed/29206240
http://dx.doi.org/10.1371/journal.ppat.1006732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736228/
https://www.ncbi.nlm.nih.gov/pubmed/29206240
http://dx.doi.org/10.1371/journal.ppat.1006732

Ejemplares similares