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Influence of an immunodominant herpes simplex virus type 1 CD8(+) T cell epitope on the target hierarchy and function of subdominant CD8(+) T cells

Herpes simplex virus type 1 (HSV-1) latency in sensory ganglia such as trigeminal ganglia (TG) is associated with a persistent immune infiltrate that includes effector memory CD8(+) T cells that can influence HSV-1 reactivation. In C57BL/6 mice, HSV-1 induces a highly skewed CD8(+) T cell repertoire...

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Detalles Bibliográficos
Autores principales:	Treat, Benjamin R., Bidula, Sarah M., Ramachandran, Srividya, St Leger, Anthony J., Hendricks, Robert L., Kinchington, Paul R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736228/ https://www.ncbi.nlm.nih.gov/pubmed/29206240 http://dx.doi.org/10.1371/journal.ppat.1006732

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