Severe infections emerge from commensal bacteria by adaptive evolution

Bacteria responsible for the greatest global mortality colonize the human microbiota far more frequently than they cause severe infections. Whether mutation and selection among commensal bacteria are associated with infection is unknown. We investigated de novo mutation in 1163 Staphylococcus aureus...

Descripción completa

Detalles Bibliográficos
Autores principales: Young, Bernadette C, Wu, Chieh-Hsi, Gordon, N Claire, Cole, Kevin, Price, James R, Liu, Elian, Sheppard, Anna E, Perera, Sanuki, Charlesworth, Jane, Golubchik, Tanya, Iqbal, Zamin, Bowden, Rory, Massey, Ruth C, Paul, John, Crook, Derrick W, Peto, Timothy E, Walker, A Sarah, Llewelyn, Martin J, Wyllie, David H, Wilson, Daniel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736351/
https://www.ncbi.nlm.nih.gov/pubmed/29256859
http://dx.doi.org/10.7554/eLife.30637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736351/
https://www.ncbi.nlm.nih.gov/pubmed/29256859
http://dx.doi.org/10.7554/eLife.30637

Ejemplares similares