Ubiquitin-Specific Protease 14 Negatively Regulates Toll-Like Receptor 4-Mediated Signaling and Autophagy Induction by Inhibiting Ubiquitination of TAK1-Binding Protein 2 and Beclin 1

Ubiquitin-specific protease 14 (USP14), one of three proteasome-associated deubiquitinating enzymes, has multifunctional roles in cellular context. Here, we report a novel molecular mechanism and function of USP14 in regulating autophagy induction and nuclear factor-kappa B (NF-κB) activation induce...

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Detalles Bibliográficos
Autores principales: Min, Yoon, Lee, Sena, Kim, Mi-Jeong, Chun, Eunyoung, Lee, Ki-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736539/
https://www.ncbi.nlm.nih.gov/pubmed/29326710
http://dx.doi.org/10.3389/fimmu.2017.01827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736539/
https://www.ncbi.nlm.nih.gov/pubmed/29326710
http://dx.doi.org/10.3389/fimmu.2017.01827

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