Cargando…

Photoreceptor metabolic reprogramming provides survival advantage in acute stress while causing chronic degeneration

Photoreceptor death is the root cause of vision loss in many retinal disorders, and there is an unmet need for neuroprotective modalities to improve photoreceptor survival. The biosynthetic requirement of photoreceptors is among the highest in the body, and to meet this demand, photoreceptors mainta...

Descripción completa

Detalles Bibliográficos
Autores principales: Wubben, Thomas J., Pawar, Mercy, Smith, Andrew, Toolan, Kevin, Hager, Heather, Besirli, Cagri G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736549/
https://www.ncbi.nlm.nih.gov/pubmed/29259242
http://dx.doi.org/10.1038/s41598-017-18098-z